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PPT
Addressing Irreproducibility Presentations: Academic Drug Discovery: Where the Rubber Meets the Road

Stephen Frye was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation. Stephen was addressing the academic and industrial drug discovery experience and solutions in this ongoing issue.

Stephen Frye is Professor and...

Center for Integrative Chemical Biology and Drug Discovery

UNC Chapel Hill

Presenter: Stephen V. Frye, Ph.D.

PPT
Addressing Irreproducibility Presentations: Data Reproducibility: An Editor’s Perspective

Angel Colmone was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation.  Angela was addressing the roles of journals in this ongoing issue. 

Angela Colmone is currently an Associate Editor for Science...

Science Translational Medicine

Presenter: Angela Colmone, Ph.D.

PPT
Addressing Irreproducibility Presentations: Defining the Problem

Shai Silberberg was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation. Shai was defining the problem to begin the symposium.

Dr. Shai D. Silberberg is a Program Director at the NIH National Institute of...

NINDS/NIH

Presenter: Shai Silberberg

PPT
Addressing Irreproducibility Presentations: Defining the Problem: Case Histories in ALS

Fernando Vieira was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation. Fernando was sharing case studies in ALS.

Fernando Vieira has worked at the ALS Therapy Development Institute since 2001 and has deep ties to...

ALS-TDI

ALS-Therapy Development Institute

Presenter: Fernando Vieira

PPT
Addressing Irreproducibility Presentations: Enhancing Reproducibility and Transparency of Research Findings: The Role of NIH

Dorit Zuk was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation. Dorit was addressing the role of the NIH in addressing this issue of
reproducibility.

Dorit Zuk is Director of the Office of Policy,...

Office of Policy, Communications and Strategic Alliances National Center for Advancing Translational Sciences (NCATS) National Institutes of Health

Presenter: Dorit Zuk, Ph.D.

PPT
Addressing Irreproducibility Presentations: Fostering research reproducibility: A Nature journal perspective


Terry Sheppard was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation.Terry was addressing the roles of journals in this ongoing issue.

Terry L. Sheppard has served as the Chief Editor of Nature Chemical Biology...

Nature Chemical Biology, Nature Publishing Group

Presenter: Terry Sheppard

PPT
Addressing Irreproducibility Presentations: The role of RNAi in early target validation

Caroline Shamu was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation.Stephen was addressing the academic and industrial drug discovery experience and solutions in this ongoing issue.

Caroline Shamu is the Director...

ICCB-Longwood Screening Facility

Harvard Medical School

Presenter: Caroline Shamu, Ph.D.

PPT
Addressing Irreproducibility Presentations: Trust but Verify: Flagging and curating chemical and biological errors in bioactivity databases


Denis Fourches was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation. Denis was addressing the Academic and Industrial Drug Discovery Experience and Solutions in this ongoing issue.

Denis Fourches is a Research...

Laboratory for Molecular Modeling

University of North Carolina at Chapel Hill

Presenter: Denis Fourches

PPT
Addressing Irreproducibility Presentations: Welcome and Outline of the Day

 Barbara Slusher and Sitta Sittampalam were the opening presenters at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation. They offered background on both the ADDC and the Assay Guidance Manual as well as meeting objectives...

Academic Drug Discovery Consortium/ Assay Guidace Manual

Johns Hopkins Brain Science Institute/ NCATS

Presenter: Barbara Slusher & G. Sitta Sittampalam

PPT
Alternative Approaches To Lead Generation

Historically, drug discovery was chiefly an empirical enterprise, with the shift to a more hypothesis-driven approach occurring in the 20th century. Whereas originally drug discovery was focused primarily on identifying therapeutically useful agents...

University of Kansas Medical Center

Presenter: S.J. Enna, Ph.D.