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PPT
Addressing Irreproducibility Presentations: Trust but Verify: Flagging and curating chemical and biological errors in bioactivity databases

Denis Fourches was a presenter at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation. Denis was addressing the Academic and Industrial Drug Discovery Experience and Solutions in this ongoing issue. Denis Fourches is a Research A...

 

Laboratory for Molecular Modeling

 

University of North Carolina at Chapel Hill

 

Presenter: Denis Fourches

PPT
Addressing Irreproducibility Presentations: Welcome and Outline of the Day

 Barbara Slusher and Sitta Sittampalam were the opening presenters at the ADDC/AGM Symposium Addressing Irreproducibility in Target Validation. They offered background on both the ADDC and the Assay Guidance Manual as well as meeting objectives ...

 

Academic Drug Discovery Consortium/ Assay Guidace Manual

 

Johns Hopkins Brain Science Institute/ NCATS

 

Presenter: Barbara Slusher & G. Sitta Sittampalam

PPT
Alternative Approaches To Lead Generation

Historically, drug discovery was chiefly an empirical enterprise, with the shift to a more hypothesis-driven approach occurring in the 20th century. Whereas originally drug discovery was focused primarily on identifying therapeutically useful agents...

 

 

University of Kansas Medical Center

 

Presenter: S.J. Enna, Ph.D.

E-Book
Assay Guidance Manual

The collection of chapters in this eBook is written to provide guidance to investigators who are interested in developing assays useful for the evaluation of collections of molecules to identify probes that modulate the activity of biological t...

 

collaboration among group of editors and writers

 

multiple

 

Presenter: Sittampalam GS, Gal-Edd N, Arkin M, Auld D, Austin C, Bejcek B, Glicksman M, Inglese J, Lemmon V, Li Z, McGee J, McManus O, Minor L, Napper A, Riss T, Trask OJ , Weidner J, editors.

Document
Big data in drug safety

Safety and efficacy information on drugs shall be communicated to all stakeholders, including physicians, patients, insurers and investors, in a format that allows objective assessment of real value of the intervention compared to other treatments. B...

 

 

ARETE-ZOE, LLC

 

Presenter: Veronika Valdova

PPT
Biopharmaceutical Development and QA/QC

This collection of biopharmaceutical applications will help you find the right solution for your analytical needs.

 

 

Agilent Technologies

 

Presenter: Agilent Technologies

PPT
Case Study: The Discovery of Telaprevir (VX-950, IncivekĀ®) for the treatment of Hepatitis C

This Case study shows the drug discovery process of Telaprevir for Hepatitis. IT discusses the background of Hepatitis, and the basic information on Hepatitis C, Preclinical studies, Clinical studies, critical findings, timeline to approval and the f...

 

Brain Science Institute NeuroTranslational Drug Discovery Program

 

Johns Hopkins University

 

Presenter: Dana Ferraris, Ph.D., M.B.A.

PPT
Changing Landscape of Drug Discovery in Industry Settings

This lecture entitled “Changing Landscape of Drug Discovery in Industry Settings” introduces the drug discovery and development process to a class focused on a range of topics related to discovery and development of new therapeutic agents and dev...

 

Vanderbilt Center for Neuroscience Drug Discovery

 

Vanderbilt University

 

Presenter: P. Jeffrey Conn

PPT
CNS Medicinal Chemistry: Introduction and a Case Study – GlyT1

This lecture will provide an overview of the drug discovery process with specific attention being paid to the role of medicinal chemistry, and key issues for the CNS disease-focused medicinal chemist (Lipinskis rules, CNS penetration, transporter as...

 

Vanderbilt Specialized Chemistry Center (MLPCN)

 

Vanderbilt University

 

Presenter: Craig W. Lindsley

PPT
Compliance for Biopharmaceutical Laboratories

This primer is intended to introduce FDA and equivalent international requirements. The primer will also give strategies and specific recommendations for regulated laboratories on how to implement the requirements in the most cost effective way.

 

 

Agilent Technologies

 

Presenter: Agilent Technologies