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PPT
Case Study: The Discovery of Telaprevir (VX-950, IncivekĀ®) for the treatment of Hepatitis C

This Case study shows the drug discovery process of Telaprevir for Hepatitis. IT discusses the background of Hepatitis, and the basic information on Hepatitis C, Preclinical studies, Clinical studies, critical findings, timeline to approval and the f...

 

Brain Science Institute NeuroTranslational Drug Discovery Program

 

Johns Hopkins University

 

Presenter: Dana Ferraris, Ph.D., M.B.A.

PPT
In Vivo Pharmacokinetics

A lecture discussing In vivo Pharmacokinetics including commonly used animals, routes of administration, blood sampling, bioanalysis, pharmacokinetics parameters, and Pharmacokinetics/Pharmacodynamics. This is the sixth lecture in a 15 week course, ⮮.

 

Brain Science Institute NeuroTranslational Drug Discovery Program

 

Johns Hopkins University

 

Presenter: Takashi Tsukamoto, Ph.D

PPT
In Vivo Pharmacology

A lecture discussing In vivo Pharmacology, the definition, rules and ethics governing animal experimentation, history, shortcomings, use in drug discovery, study design considerations, and specific examples of some disease models.This is the eighth l...

 

Brain Science Institute NeuroTranslational Drug Discovery Program

 

Johns Hopkins University

 

Presenter: Krystyna Wozniak, Ph.D.

PPT
It’s all about dose…. Toxicology in Drug Discovery and Development

Nonclinical toxicology studies are critical during drug development due to the scientific need and regulatory requirement to collect information to define the toxicity profile and provide an evaluation of the relationship of dose and exposure to toxi...

 

 

Ironwood Pharmaceticals

 

Presenter: Adaline C. Smith, PhD, DABT