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PPT
A High-Throughput, Accurate Mass Approach for Plasma Protein Binding Analysis Using SPE/TOF-MS

An ultafast SPE/TOF/MS method was developed to analyze plasma protein binding assay samples at a rate of 9 sec per sample. This ultrafast, high resolution approach may be useful for the analysis of other in vitro ADME assays

 

 

Agilent Technologies

 

Presenter: Agilent Technologies

PPT
Case Study: The Discovery of Telaprevir (VX-950, IncivekĀ®) for the treatment of Hepatitis C

This Case study shows the drug discovery process of Telaprevir for Hepatitis. IT discusses the background of Hepatitis, and the basic information on Hepatitis C, Preclinical studies, Clinical studies, critical findings, timeline to approval and the f...

 

Brain Science Institute NeuroTranslational Drug Discovery Program

 

Johns Hopkins University

 

Presenter: Dana Ferraris, Ph.D., M.B.A.

PPT
In Vitro Pharmacokinetics

A lecture discussing In vitro Pharmacokinetics assays including permeability, metabolism, drug-drug interaction, and protein binding.This is the fifth lecture in a 15 week course, “Introduction to Drug Discovery Research”, given at Johns Hopkins ...

 

Brain Science Institute NeuroTranslational Drug Discovery Program

 

Johns Hopkins University

 

Presenter: Takashi Tsukamoto, Ph.D.

PPT
In Vivo Pharmacokinetics

A lecture discussing In vivo Pharmacokinetics including commonly used animals, routes of administration, blood sampling, bioanalysis, pharmacokinetics parameters, and Pharmacokinetics/Pharmacodynamics. This is the sixth lecture in a 15 week course, ⮮.

 

Brain Science Institute NeuroTranslational Drug Discovery Program

 

Johns Hopkins University

 

Presenter: Takashi Tsukamoto, Ph.D

PPT
Lead Optimization

A lecture on hit to lead and lead optimization. This is the tenth lecture in a 15 week course, given at Johns Hopkins University School of Medicine, discussing the various aspects of the Drug Discovery process. The course is directed by Dr. Takash...

 

Brain Science Institute NeuroTranslational Drug Discovery Program

 

Johns Hopkins University

 

Presenter: Takashi Tsukamoto, Ph.D.

PPT
Rapid and Robust Early ADME Solutions

By eliminating compounds with toxic liabilities during discovery, instead of during clinical development, more resources can be focused on compounds with a greater likelihood of success. Agilent presents rapid and robust solutions for early ADME stud...

 

 

Agilent Technologies

 

Presenter: Agilent Technologies

PPT
The Small Molecule Discovery Center

This presentation introduces the Small Molecule Discovery Center at UCSF, and describes the center’s goals, philosophy, and examples of projects. Several different approaches to interacting with pharmaceutical companies are also summarized.

 

Small Molecule Discovery Center

 

University of California San Francisco

 

Presenter: Michelle Arkin