Molecular Targets Laboratory

Therapeutic Approaches: Small Molecules

Therapeutic Areas of Expertise: Infectious Diseases, Oncology

Center/Program Highlights: The MTL provides leadership for the translation of basic science advances into drug leads, bioprobes and reagents for molecular target evaluation. The Lab exploits chemical and biodiversity repositories, including the NCI Natural Products Repository, for molecularly-targeted lead discovery; and facilitates the discovery of natural products and synthetic compounds that may serve as bioprobes for chemical genetics, proteomics, target validation and potential lead compounds for clinical development. Compounds of interest include not only classical, "drug-like" organic small molecules, but also peptides, proteins, and other bioactive chemical classes.

Sources of Funding: Federal/State

Website

Institutional Affiliation(s): Center for Cancer Research National Cancer Institute

Address:
NCI-Frederick
Bldg 560 Rm 11-67
Frederick
Maryland, 21702
United States

Center/Program Start Date: 2001

Number of Employees: 35